Mouse Secondary Antibodies
Biotium Human IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker) (IGHD/2730R), CF568 conjugate, 0.1mg/mL
Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer withδ heavy chains and either κ or λ light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability.
Biolegend Ultra-LEAF Purified anti-human CD309 (VEGFR2) [W21067C] Isotype Rat IgG2a Reactivity Human Apps Block Size 100 ug
Ultra-LEAF Purified anti-human CD309 (VEGFR2) [W21067C] Isotype Rat IgG2a Reactivity Human Apps Block Size 100 ug
Biotang Inc CD4-FITC, Mouse Anti-Human, CD4 FITC Antibody, Mouse Anti Human Monoclonal.
CD4-FITC, Mouse Anti-Human, CD4 FITC Antibody, Mouse Anti Human Monoclonal.
Biolegend Spark RedTM 718 anti-mouse CD1
Spark Red 718 anti-mouse CD16/32 [93] Isotype Rat IgG2a Reactivity Mouse Apps FC Size 100 g
Biolegend Spark PLUS B550TM anti-mouse C
Spark PLUS B550™ anti-mouse CD279 (PD-1) [29F.1A12]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 25 μg
Cayman Chemical Senae folIum SenIdIn A 10mg
An active metabolite of sennoside A; formed from sennoside A by gut microbiota; increases fecal excretion in mice
American Research Products Inc Mouse AntiPD1
Mouse Anti-PD-1 (CD279) Fc Reduced (LALA-PG) Recombinant Monoclonal Antibody is a in vivo antibody with mouse reactivity produced in mouse-rat chimeric Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
Genscript Corporation CTLA-4 Fc Chimera Mouse
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 is an Inhibitory receptor acting as a major negative regulator of T-cell responses CTLA-4 is a member of the immunoglobulin superfamily which is expressed on the surface of T cells and transmits an inhibitory signal to T cells CTLA-4 and CD28 are homologous receptors expressed by both CD4 and CD8 T cells which mediate opposing functions in T-cell activation Both receptors share a pair of ligands expressed on the surface of antigen-presenting cells (APCs) The affinity of CTLA-4 for its natural B7 family ligands CD80 and CD86 is considerably stronger than the affinity of their cognate stimulatory co-receptor CD28
Cayman Chemical Mouse PRoxIsome ProlIfRatr 96
mPPARδ Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments. [INDIGO Catalog Nos. M00121-32, M00121]
Cayman Chemical WIlforlIde A 50mg
A triterpene; inhibits xylene-induced EAr swelling in mice at 60 or 300 UG/kg; reduces inflammation, bone damage, and synovial hyperplasia in the inflamed joints in a rat model of collagen-induced arthritis in combination with triptolide
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-ATG16L1 (Ser278) Detection Kit, Control Lysate
HTRF Human & Mouse Phospho-ATG16L1 (Ser278) Detection Kit, Control Lysate
ATCC YUMM1.7; Melanoma; Mouse (Mus musculus)
YUMM1.7 is a cell line with epithelial-like morphology isolated in 2014 from the skin of an adult male mouse with melanoma. This cell line is genetically modified containing human-relevant mutations like BrafV600E/wt (knock in conditionally activated Braf allele), Cdkn2a-/- Pten-/- (conditionally inactivated). It also has Tyrosinase:CreERT2 transgene, which restricts recombination to melanocytes. It was deposited by the Yale University School of Medicine.
Biotium Human IgG4 (Ig Heavy Constant Gamma 4) (G4m Marker) (IGHG4/1345), CF740 conjugate, 0.1mg/mL
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells. IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibrobl
Sino Biological Rabbit Anti-Mouse IgG1 Secondary Antibody (HRP), Rabbit MAb 20 µg
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IgG1 (rM IgG1; Catalog# 10690-MNAH; P01868-1; Val98-Lys324,C102S), and conjugated with horseradish-peroxidase (HRP).